The Profiles of Tet-Mediated DNA Hydroxymethylation in Human Gliomas

The Profiles of Tet-Mediated DNA Hydroxymethylation in Human Gliomas

Gliomas are the most common primary malignant intracranial brain tumors. Their proliferative and invasive behavior is controlled by various epigenetic mechanisms. 5-hydroxymethylcytosine (5-hmC) is one of the epigenetic DNA modifications that employs ten-eleven translocation (TET) enzymes to its oxi...

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Bibliographic Details
Main Authors: Aneta Brągiel-Pieczonka, Gabriela Lipka, Angelika Stapińska-Syniec, Michał Czyżewski, Katarzyna Żybura-Broda, Michał Sobstyl, Marcin Rylski, Marta Grabiec
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
epigenetics
5-hydroxymethylcytosine
ten-eleven translocation enzymes
brain tumors
glioblastoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.621460/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.621460/full

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