Metagenomic Next-Generation Sequencing for Diagnosis of Infectious Encephalitis and Meningitis: A Large, Prospective Case Series of 213 Patients

Metagenomic Next-Generation Sequencing for Diagnosis of Infectious Encephalitis and Meningitis: A Large, Prospective Case Series of 213 Patients

Purpose: We assessed the performance of metagenomic next-generation sequencing (mNGS) in the diagnosis of infectious encephalitis and meningitis.Methods: This was a prospective multicenter study. Cerebrospinal fluid samples from patients with viral encephalitis and/or meningitis, tuberculous meningi...

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Bibliographic Details
Main Authors: Xiao-Wei Xing, Jia-Tang Zhang, Yu-Bao Ma, Mian-Wang He, Guo-En Yao, Wei Wang, Xiao-Kun Qi, Xiao-Yan Chen, Lei Wu, Xiao-Lin Wang, Yong-Hua Huang, Juan Du, Hong-Fen Wang, Rong-Fei Wang, Fei Yang, Sheng-Yuan Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
encephalitis
meningitis
pathogens
metagenomic next-generation sequencing
diagnosis
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00088/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.00088/full

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