Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins

Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins

Cliff Luke et al. report that lysoptosis is a eukaryotic stand-alone regulated cell death pathway. They identify that this new cell death modality predominates in the absence of neutralizing endogenous inhibitors.

Bibliographic Details
Main Authors: Cliff J. Luke, Stephanie Markovina, Misty Good, Ira E. Wight, Brian J. Thomas, John M. Linneman, Wyatt E. Lanik, Olga Koroleva, Maggie R. Coffman, Mark T. Miedel, Qingqing Gong, Arlise Andress, Marlene Campos Guerrero, Songyan Wang, LiYun Chen, Wandy L. Beatty, Kelsey N. Hausmann, Frances V. White, James A. J. Fitzpatrick, Anthony Orvedahl, Stephen C. Pak, Gary A. Silverman
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02953-x

Internet

https://doi.org/10.1038/s42003-021-02953-x

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