Structure of the C-terminal Region of the Frizzled Receptor 1 in Detergent Micelles
The C-terminal domains of the Frizzleds (FZDs) contain a short conserved motif (KTXXXW). It has been demonstrated that FZDs interacted with the PDZ domain of the cytoplasmic proteins such as Dishevelled through this motif and mutations in this motif disrupted Wnt/β-catenin signaling. We carried out...
| Hauptverfasser: | , , , |
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| Format: | Artikel |
| Sprache: | English |
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MDPI AG
2013-07-01
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| Schriftenreihe: | Molecules |
| Schlagworte: | |
| Online Zugang: | http://www.mdpi.com/1420-3049/18/7/8579 |