Upregulation of CD11A on Hematopoietic Stem Cells Denotes the Loss of Long-Term Reconstitution Potential

Small numbers of hematopoietic stem cells (HSCs) generate large numbers of mature effector cells through the successive amplification of transiently proliferating progenitor cells. HSCs and their downstream progenitors have been extensively characterized based on their cell-surface phenotype and fun...

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Bibliographic Details
Main Authors: John W. Fathman, Nathaniel B. Fernhoff, Jun Seita, Connie Chao, Vanessa M. Scarfone, Irving L. Weissman, Matthew A. Inlay
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114002926