Effects of CYP2C19 genetic polymorphisms on the cure rates of H. pylori in patients treated with the proton pump inhibitors: An updated meta-analysis

Effects of CYP2C19 genetic polymorphisms on the cure rates of H. pylori in patients treated with the proton pump inhibitors: An updated meta-analysis

Background: The cure rates of Helicobacter pylori (H. pylori) treatment using a proton pump inhibitor (PPI) are gradually decreasing due to antibiotic resistance, poor compliance, high gastric acidity, and cytochrome P450 2C19 (CYP2C19) polymorphism, and the effects of PPI depend on metabolic enzyme...

Full description

Bibliographic Details
Main Authors: Xianghong Zhao, Zhongqiu Zhang, Fang Lu, Mengqiu Xiong, Liping Jiang, Ke Tang, Min Fu, Yu Wu, Bangshun He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
Helicobacter pylori
eradication rate
genetic polymorphisms
CYP2C19
meta- analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.938419/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.938419/full

Similar Items