Proline restores mitochondrial function and reverses aging hallmarks in senescent cells

Proline restores mitochondrial function and reverses aging hallmarks in senescent cells

Summary: Mitochondrial dysfunction is a hallmark of cellular senescence, with the loss of mitochondrial function identified as a potential causal factor contributing to senescence-associated decline in cellular functions. Our recent findings revealed that ectopic expression of the pluripotency trans...

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Bibliographic Details
Main Authors: Debanik Choudhury, Na Rong, Hamsa Vardini Senthil Kumar, Sydney Swedick, Ronel Z. Samuel, Pihu Mehrotra, John Toftegaard, Nika Rajabian, Ramkumar Thiyagarajan, Ashis K. Podder, Yulun Wu, Shahryar Shahini, Kenneth L. Seldeen, Bruce Troen, Pedro Lei, Stelios T. Andreadis
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
CP: Cell biology
CP: Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724000664

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http://www.sciencedirect.com/science/article/pii/S2211124724000664

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