Key factors to establish the ovalbumin-induced atopic dermatitis minipig model: age and body weight

Key factors to establish the ovalbumin-induced atopic dermatitis minipig model: age and body weight

Abstract Background Given its similar structure and immune response to the human skin, porcine is a good model for dermal studies. Here, we sensitized ovalbumin (Ova) on minipig back skin for 2–4 weeks to induce chronic atopic dermatitis (AD). Results Gross observation, serum cytokine level, epiderm...

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Bibliographic Details
Main Authors: Young Kyu Kim, JuKyung Lee, Hyeon-Young Kim, Sung-Hwan Kim, Jeong Ho Hwang, Han Na Suh
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Laboratory Animal Research
Subjects:
Yucatan minipig
Atopic dermatitis
Ovalbumin
Age/body weight
Dermal thickness
Online Access:https://doi.org/10.1186/s42826-022-00141-4

Internet

https://doi.org/10.1186/s42826-022-00141-4

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