Amino Derivatives of Diaryl Pyrimidines and Azolopyrimidines as Protective Agents against LPS-Induced Acute Lung Injury

Amino Derivatives of Diaryl Pyrimidines and Azolopyrimidines as Protective Agents against LPS-Induced Acute Lung Injury

The problem of lung damage originating from excessive inflammation and cytokine release during various types of infections remains relevant and stimulates the search for highly effective and safe drugs. The biological activity of the latter may be associated with the regulation of hyperactivation of...

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Bibliographic Details
Main Authors: Alexander Spasov, Irina Ovchinnikova, Olga Fedorova, Yulia Titova, Denis Babkov, Vadim Kosolapov, Alexander Borisov, Elena Sokolova, Vladlen Klochkov, Maria Skripka, Yulia Velikorodnaya, Alexey Smirnov, Gennady Rusinov, Valery Charushin
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
pyrimidines
[1,2,4]triazolo[1,5-<i>a</i>]pyrimidines
inflammation
lung injury
cytokine release
Online Access:https://www.mdpi.com/1420-3049/28/2/741

Internet

https://www.mdpi.com/1420-3049/28/2/741

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