Isolation, identification and structural characterization of forced degradation products of mobocertinib using LC-MS/MS and NMR

Isolation, identification and structural characterization of forced degradation products of mobocertinib using LC-MS/MS and NMR

The main objective of this study is to develop and validate an LC-MS/MS stability-indicating method for the isolation, identification, and characterization of forced degradation products of mobocertinib under various stress conditions, utilizing LC-MS/MS and NMR techniques. Four degradation products...

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Bibliographic Details
Main Authors: Shweta Mishra, Ashlesha Chauhan, R. Ramajayam
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Results in Chemistry
Subjects:
Mobocertinib
Method development
Validation
Forced degradation studies
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624001619

Internet

http://www.sciencedirect.com/science/article/pii/S2211715624001619

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