A single mild juvenile TBI in male mice leads to regional brain tissue abnormalities at 12 months of age that correlate with cognitive impairment at the middle age

A single mild juvenile TBI in male mice leads to regional brain tissue abnormalities at 12 months of age that correlate with cognitive impairment at the middle age

Abstract Traumatic brain injury (TBI) has the highest incidence amongst the pediatric population and its mild severity represents the most frequent cases. Moderate and severe injuries as well as repetitive mild TBI result in lasting morbidity. However, whether a single mild TBI sustained during chil...

Full description

Bibliographic Details
Main Authors: Andre Obenaus, Beatriz Rodriguez-Grande, Jeong Bin Lee, Christophe J. Dubois, Marie-Line Fournier, Martine Cador, Stéphanie Caille, Jerome Badaut
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Acta Neuropathologica Communications
Subjects:
Mild TBI
Basal forebrain/cholinergic system
Hippocampus
AQP4
DTI
Memory
Online Access:https://doi.org/10.1186/s40478-023-01515-y

Internet

https://doi.org/10.1186/s40478-023-01515-y

Similar Items