Paired image‐ and FACS‐based toxicity assays for high content screening of spheroid‐type tumor cell cultures

Paired image‐ and FACS‐based toxicity assays for high content screening of spheroid‐type tumor cell cultures

Novel spheroid‐type tumor cell cultures directly isolated from patients’ tumors preserve tumor characteristics better than traditionally grown cell lines. However, such cultures are not generally used for high‐throughput toxicity drug screens. In addition, the assays that are commonly used to assess...

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Bibliographic Details
Main Authors: Kari Trumpi, David A. Egan, Thomas T. Vellinga, Inne H.M. Borel Rinkes, Onno Kranenburg
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:FEBS Open Bio
Subjects:
Toxicity assay
High-throughput
Spheroid-type tumor cell culture
Online Access:https://doi.org/10.1016/j.fob.2015.01.003

Internet

https://doi.org/10.1016/j.fob.2015.01.003

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