Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice

Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice

<p>Abstract</p> <p>Background</p> <p>Familial Alzheimer's disease-linked variants of presenilin (PSEN1 and PSEN2) contribute to the pathophysiology of disease by both gain-of-function and loss-of-function mechanisms. Deletions of <it>PSEN1 </it>and <...

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Bibliographic Details
Main Authors: Choi Se, Garbett Krassimira, Norstrom Eric M, Mirnics Károly, Zhang Xiaoqiong, Ebert Philip, Sisodia Sangram S
Format: Article
Language:English
Published: BMC 2008-10-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/3/1/14

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http://www.molecularneurodegeneration.com/content/3/1/14

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