Ultrasound-Assisted Synthesis and In Silico Modeling of Methanesulfonyl-Piperazine-Based Dithiocarbamates as Potential Anticancer, Thrombolytic, and Hemolytic Structural Motifs

Ultrasound-Assisted Synthesis and In Silico Modeling of Methanesulfonyl-Piperazine-Based Dithiocarbamates as Potential Anticancer, Thrombolytic, and Hemolytic Structural Motifs

Piperazine-based dithiocarbamates serve as important scaffolds for numerous pharmacologically active drugs. The current study investigates the design and synthesis of a series of dithiocarbamates with a piperazine unit as well as their biological activities. Under ultrasound conditions, the correspo...

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Bibliographic Details
Main Authors: Freeha Hafeez, Ameer Fawad Zahoor, Azhar Rasul, Asim Mansha, Razia Noreen, Zohaib Raza, Kulsoom Ghulam Ali, Ali Irfan, Gamal A. El-Hiti
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
anticancer
piperazine dithiocarbamates
hemolysis
in silico modeling
lung carcinoma
ultrasound
Online Access:https://www.mdpi.com/1420-3049/27/15/4776

Internet

https://www.mdpi.com/1420-3049/27/15/4776

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