β2-Microglobulin exacerbates neuroinflammation, brain damage, and cognitive impairment after stroke in rats

β2-Microglobulin exacerbates neuroinflammation, brain damage, and cognitive impairment after stroke in rats

β2-Microglobulin (β2M), a component of the major histocompatibility complex class I molecule, is associated with aging-related cognitive impairment and Alzheimer’s disease. Although upregulation of β2M is considered to be highly related to ischemic stroke, the specific role and underlying mechanisti...

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Bibliographic Details
Main Authors: Feng Chen, Jing Liu, Fa-Qiang Li, Shuai-Shuai Wang, Yan-Yan Zhang, Yun-Yun Lu, Fang-Fang Hu, Rui-Qin Yao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
cognitive impairment; cognitive improvement; glial activation; infarct volume; ischemia; middle cerebral artery occlusion; neuroinflammation; nlrp3 inflammasome; stroke; β2 microglobulin
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=3;spage=603;epage=608;aulast=Chen

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=3;spage=603;epage=608;aulast=Chen

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