Synthesis and Biological Activity of Novel α-Conotoxins Derived from Endemic Polynesian Cone Snails

Synthesis and Biological Activity of Novel α-Conotoxins Derived from Endemic Polynesian Cone Snails

α-Conotoxins are well-known probes for the characterization of the various subtypes of nicotinic acetylcholine receptors (nAChRs). Identifying new α-conotoxins with different pharmacological profiles can provide further insights into the physiological or pathological roles of the numerous nAChR isof...

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Bibliographic Details
Main Authors: Yazid Mohamed Souf, Gonxhe Lokaj, Veeresh Kuruva, Yakop Saed, Delphine Raviglione, Ashraf Brik, Annette Nicke, Nicolas Inguimbert, Sébastien Dutertre
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Marine Drugs
Subjects:
conotoxin
peptide synthesis
two-electrode voltage clamp
nicotinic acetylcholine receptors
Online Access:https://www.mdpi.com/1660-3397/21/6/356

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https://www.mdpi.com/1660-3397/21/6/356

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