Targeted depletion of pks+ bacteria from a fecal microbiota using specific antibodies

ABSTRACT The pks island is one of the most prevalent pathogenicity islands among the Escherichia coli strains that colonize the colon of colorectal carcinoma (CRC) patients. This pathogenic island encodes the production of a nonribosomal polyketide-peptide named colibactin, which induces double-stra...

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Bibliographic Details
Main Authors: Aitor Blanco-Míguez, Raquel Marcos-Fernández, Lucía Guadamuro-García, Florentino Fdez-Riverola, Joaquín Cubiella, Anália Lourenço, Abelardo Margolles, Borja Sánchez
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msystems.00079-23