Molecular Conformations and Biological Activity of <i>N</i>-Hetaryl(aryl)alkyl-4-methyl-2,2-dioxo-1<i>H</i>-2λ<sup>6</sup>,1-benzothiazine-3-carboxamides

Molecular Conformations and Biological Activity of <i>N</i>-Hetaryl(aryl)alkyl-4-methyl-2,2-dioxo-1<i>H</i>-2λ<sup>6</sup>,1-benzothiazine-3-carboxamides

The analysis of our previous studies on the search for synthetic analgesics among <i>N</i>-R-amides of bicyclic hetaryl-3-carboxylic acids has been performed; on its basis <i>N</i>-hetaryl(aryl)-alkyl-4-methyl-2,2-dioxo-1<i>H</i>-2&#955;<sup>6</sup>...

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Bibliographic Details
Main Authors: Igor V. Ukrainets, Ganna M. Hamza, Anna A. Burian, Natali I. Voloshchuk, Oxana V. Malchenko, Svitlana V. Shishkina, Lina A. Grinevich, Vasyl V. Grynenko, Galina Sim
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Scientia Pharmaceutica
Subjects:
4-methyl-2,2-dioxo-1<i>H</i>-2λ<sup>6</sup>,1-benzothiazine-3-carboxylamide
2,1-benzothiazine
crystal structure
molecular conformation
analgesic activity
anti-inflammatory action
Online Access:https://www.mdpi.com/2218-0532/86/4/50

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https://www.mdpi.com/2218-0532/86/4/50

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