Convergence of Rad6/Rad18 and Fanconi anemia tumor suppressor pathways upon DNA damage.

Extremely high cancer incidence associated with patients with Fanconi anemia (FA) suggests the importance of the FA signaling pathway in the suppression of non-FA human tumor development. Indeed, we found that an impaired FA signaling pathway substantially contributes to the development of non-FA hu...

Full description

Bibliographic Details
Main Authors: Hwan Ki Park, Hong Wang, Jun Zhang, Suvamoy Datta, Peiwen Fei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2954165?pdf=render