Application of cryo-electron microscopy for investigation of Bax-induced pores in apoptosis
Mitochondrial outer membrane permeabilization (MOMP) is a critical step in apoptosis, the molecular mechanisms of which have been a subject of intensive study. This process is important for therapeutic intervention in various diseases, such as cancer. Pro-apoptotic Bax and Bak are functionally redun...
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| Format: | Article |
| Language: | English |
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De Gruyter
2017-02-01
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| Series: | Nanotechnology Reviews |
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| Online Access: | https://doi.org/10.1515/ntrev-2016-0070 |