Synthesis of Novel Lipophilic Polyamines via Ugi Reaction and Evaluation of Their Anticancer Activity

Synthesis of Novel Lipophilic Polyamines via Ugi Reaction and Evaluation of Their Anticancer Activity

Natural polyamines (PAs) are involved in the processes of proliferation and differentiation of cancer cells. Lipophilic synthetic polyamines (LPAs) induce the cell death of various cancer cell lines. In the current paper, we have demonstrated a new method for synthesis of LPAs via the multicomponent...

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Bibliographic Details
Main Authors: Artemiy Nichugovskiy, Varvara Maksimova, Ekaterina Trapeznikova, Elizaveta Eshtukova-Shcheglova, Igor Ivanov, Marianna Yakubovskaya, Kirill Kirsanov, Dmitry Cheshkov, Gian Cesare Tron, Mikhail Maslov
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
polyamines
multicomponent Ugi reaction
lipophilic polyamines
anticancer activity
Online Access:https://www.mdpi.com/1420-3049/27/19/6218

Internet

https://www.mdpi.com/1420-3049/27/19/6218

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