A Nanoparticle-Based Affinity Sensor that Identifies and Selects Highly Cytokine-Secreting Cells

Summary: We developed a universal method termed OnCELISA to detect cytokine secretion from individual cells by applying a capture technology on the cell membrane. OnCELISA uses fluorescent magnetic nanoparticles as assay reporters that enable detection on a single-cell level in microscopy and flow c...

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Bibliographic Details
Main Authors: Guozhen Liu, Christina Bursill, Siân P. Cartland, Ayad G. Anwer, Lindsay M. Parker, Kaixin Zhang, Shilun Feng, Meng He, David W. Inglis, Mary M. Kavurma, Mark R. Hutchinson, Ewa M. Goldys
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004219303578