Primary TSC2<sup>-/meth</sup> Cells Induce Follicular Neogenesis in an Innovative TSC Mouse Model

Primary TSC2<sup>-/meth</sup> Cells Induce Follicular Neogenesis in an Innovative TSC Mouse Model

Cutaneous lesions are one of the hallmarks of tuberous sclerosis complex (TSC), a genetic disease in which mTOR is hyperactivated due to the lack of hamartin or tuberin. To date, novel pharmacological treatments for TSC cutaneous lesions that are benign but still have an impact on a patient’s life a...

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Bibliographic Details
Main Authors: Clara Bernardelli, Eloisa Chiaramonte, Silvia Ancona, Silvia M. Sirchia, Amilcare Cerri, Elena Lesma
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
tuberous sclerosis complex
primary cells
follicular neogenesis
cellular migration
mTOR
5-azacytidine
Online Access:https://www.mdpi.com/1422-0067/23/17/9713

Internet

https://www.mdpi.com/1422-0067/23/17/9713

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