Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1

Polarized localization of phosphatidylserine in the endothelium regulates Kir2.1

Lipid regulation of ion channels is largely explored using in silico modeling with minimal experimentation in intact tissue; thus, the functional consequences of these predicted lipid-channel interactions within native cellular environments remain elusive. The goal of this study is to investigate ho...

Full description

Bibliographic Details
Main Authors: Claire A. Ruddiman, Richard Peckham, Melissa A. Luse, Yen-Lin Chen, Maniselvan Kuppusamy, Bruce A. Corliss, P. Jordan Hall, Chien-Jung Lin, Shayn M. Peirce, Swapnil K. Sonkusare, Robert P. Mecham, Jessica E. Wagenseil, Brant E. Isakson
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-05-01
Series:JCI Insight
Subjects:
Vascular biology
Online Access:https://doi.org/10.1172/jci.insight.165715

Internet

https://doi.org/10.1172/jci.insight.165715

Similar Items