Rapid visualization of Clostridioides difficile toxins A and B by multiplex RPA combined with CRISPR-Cas12a

Rapid visualization of Clostridioides difficile toxins A and B by multiplex RPA combined with CRISPR-Cas12a

PurposeClostridioides difficile (C. difficile) infection is the most common cause of nosocomial infection, which is a severe challenge in modern medical care. Currently, many laboratory diagnostic methods for C. difficile are available, such as PCR, culture-based tests, and antigen-based tests. Howe...

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Bibliographic Details
Main Authors: Tong Jiang, Xinyi Hu, Chunhui Lin, Zhaoxin Xia, Wensu Yang, Yi Zhu, Huaming Xu, Hao Tang, Jilu Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Microbiology
Subjects:
Clostridioides difficile
toxin gene
recombinase polymerase amplification
CRISPR/Cas12a
lateral flow strip
point-of-care testing
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1119395/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1119395/full

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