SARS-CoV-2-specific T cells associate with inflammation and reduced lung function in pulmonary post-acute sequalae of SARS-CoV-2.

As of January 2022, at least 60 million individuals are estimated to develop post-acute sequelae of SARS-CoV-2 (PASC) after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While elevated levels of SARS-CoV-2-specific T cells have been observed in non-specific PASC, littl...

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Bibliographic Details
Main Authors: Katherine M Littlefield, Renée O Watson, Jennifer M Schneider, Charles P Neff, Eiko Yamada, Min Zhang, Thomas B Campbell, Michael T Falta, Sarah E Jolley, Andrew P Fontenot, Brent E Palmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010359