Anti-Ischemic Effects of PIK3IP1 Are Mediated through Its Interactions with the ET<sub>A</sub>-PI3Kγ-AKT Axis

Anti-Ischemic Effects of PIK3IP1 Are Mediated through Its Interactions with the ET<sub>A</sub>-PI3Kγ-AKT Axis

Oxidative stress, caused by the accumulation of reactive oxygen species (ROS) during acute myocardial infarction (AMI), is one of the main factors leading to myocardial cell damage and programmed cell death. Phosphatidylinositol-3-kinase-AKT (PI3K-AKT) signaling is essential for regulating cell prol...

Full description

Bibliographic Details
Main Authors: Jei Hyoung Park, Kyoung Jin Nho, Ji Young Lee, Yung Joon Yoo, Woo Jin Park, Chunghee Cho, Do Han Kim
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
myocardial infarction
ROS
PI3Kγ
PIK3IP1
endothelin receptor A
AKT
Online Access:https://www.mdpi.com/2073-4409/11/14/2162

Internet

https://www.mdpi.com/2073-4409/11/14/2162

Similar Items