Sulforaphane improves cognitive dysfunction after surgery and anesthesia in mice: The role of Keap1-Nrf2 signaling

Sulforaphane improves cognitive dysfunction after surgery and anesthesia in mice: The role of Keap1-Nrf2 signaling

Anesthesia and surgery are likely causing cognitive dysfunction in patients, especially the elderly. However, the underlying pathogenic mechanisms largely remain unclear. Accumulating evidence suggest that signaling between Kelch-like erythroid cell-derived protein with CNC homology (ECH)-associated...

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Bibliographic Details
Main Authors: Dongyu Hua, Ailin Luo, Zifeng Wu, Chaoli Huang, Shan Li, Xiaolin Xu, Jiali Xu, Chun Yang, Di Wang, Cunming Liu
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Brain Research Bulletin
Subjects:
Sulforaphane
Keap1-Nrf2 signaling
POCD
Anesthesia
Surgery
Mouse
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923022000089

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http://www.sciencedirect.com/science/article/pii/S0361923022000089

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