Astrogliosis Releases Pro-Oncogenic Chitinase 3-Like 1 Causing MAPK Signaling in Glioblastoma

Although reactive astrocytes constitute a major component of the cellular environment in glioblastoma, their function and crosstalk to other components of the environment is still poorly understood. Gene expression analysis of purified astrocytes from both the tumor core and non-infiltrated cortex r...

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Bibliographic Details
Main Authors: Julian Wurm, Simon P. Behringer, Vidhya M. Ravi, Kevin Joseph, Nicolas Neidert, Julian P. Maier, Roberto Doria-Medina, Marie Follo, Daniel Delev, Dietmar Pfeifer, Jürgen Beck, Roman Sankowski, Oliver Schnell, Dieter H. Heiland
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/10/1437