HOXA9 gene promotor methylation and copy number variation of SOX2 and HV2 genes in cell free DNA: A potential diagnostic panel for non-small cell lung cancer

Abstract Background Most cases of lung cancer are diagnosed at advanced stage. Detection of genetic and epigenetic markers in cell-free DNA (cfDNA) is a promising tool for the diagnosis of lung cancer at an early stage. The aim of this study was to identify non-invasive diagnostic markers in cell fr...

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Bibliographic Details
Main Authors: Abla Abou-Zeid, Doaa Hashad, Ayman Baess, Mai Mosaad, Eman Tayae
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-10793-7