A Heterozygous Missense Variant in <i>MAP2K2</i> in a Stillborn Romagnola Calf with Skeletal-Cardio-Enteric Dysplasia

A Heterozygous Missense Variant in <i>MAP2K2</i> in a Stillborn Romagnola Calf with Skeletal-Cardio-Enteric Dysplasia

RASopathies are a group of developmental disorders caused by dominant mutations in genes that encode components of the Ras/mitogen-activated protein kinase (MAPK) cell signaling pathway. The goal of this study was to characterize the pathological phenotype of a Romagnola stillborn calf with skeletal...

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Bibliographic Details
Main Authors: Joana G. P. Jacinto, Irene M. Häfliger, Arcangelo Gentile, Cord Drögemüller
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Animals
Subjects:
cattle
cardiac defect
development
congenital malformations
heterotopy
precision medicine
Online Access:https://www.mdpi.com/2076-2615/11/7/1931

Internet

https://www.mdpi.com/2076-2615/11/7/1931

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