Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin.

Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to Daunorubicin.

RNA-binding protein Musashi-2 (Msi2) is known to play a critical role in leukemogenesis and contributes to poor clinical prognosis in acute myeloid leukemia (AML). However, the effect of Msi2 silencing on treatment for AML still remains poorly understood. In this study, we used lentivirus-mediated R...

Full description

Bibliographic Details
Main Authors: Yixiang Han, Aifang Ye, Yan Zhang, Zhimin Cai, Wei Wang, Lan Sun, Songfu Jiang, Jianbo Wu, Kang Yu, Shenghui Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4550418?pdf=render

Internet

http://europepmc.org/articles/PMC4550418?pdf=render

Similar Items