Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse

Abstract To better understand the molecular mechanisms of tendon healing, we investigated the Murphy Roth’s Large (MRL) mouse, which is considered a model of mammalian tissue regeneration. We show that compared to C57Bl/6J (C57) mice, injured MRL tendons have reduced fibrotic adhesions and cellular...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Jacob G. Kallenbach, Margaret A. T. Freeberg, David Abplanalp, Rahul G. Alenchery, Raquel E. Ajalik, Samantha Muscat, Jacquelyn A. Myers, John M. Ashton, Alayna Loiselle, Mark R. Buckley, Andre J. van Wijnen, Hani A. Awad
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Portfolio 2022-02-01
श्रृंखला:Scientific Reports
ऑनलाइन पहुंच:https://doi.org/10.1038/s41598-022-07124-4