Plasma Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) in the Acute Respiratory Distress Syndrome

Plasma Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) in the Acute Respiratory Distress Syndrome

BackgroundProprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that is a mediator of the immune response to sepsis. PCSK9 is also highly expressed in pneumocytes and pulmonary endothelial cells. We hypothesized that serum PCSK9 levels would be associated with death and ICU outc...

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Bibliographic Details
Main Authors: Thomas S. Metkus, Bo Soo Kim, Steven R. Jones, Seth S. Martin, Steven P. Schulman, Thorsten M. Leucker
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Medicine
Subjects:
PCSK9 (proprotein convertase subtilisin kexin type 9)
ARDS (acute respiratory disease syndrome)
critical illness *mortality
ventilator free days
sepsis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.876046/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.876046/full

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