Stereoselective α-fluoroamide and α-fluoro-γ-lactone synthesis by an asymmetric zwitterionic aza-Claisen rearrangement

Background<p>Asymmetric introduction of fluorine α-to a carbonyl has become popular recently, largely because the direct fluorination of enolates by asymmetric electrophilic fluorinating reagents has improved, and as a result such compounds are becoming attractive synthons. We have sought an a...

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Bibliographic Details
Main Authors: Kenny Tenza, Julian S. Northen, David O'Hagan, Alexandra M. Z. Slawin
Format: Article
Language:English
Published: Beilstein-Institut 2005-10-01
Series:Beilstein Journal of Organic Chemistry
Online Access:https://doi.org/10.1186/1860-5397-1-13