Silencing LINC00987 ameliorates adriamycin resistance of acute myeloid leukemia via miR-4458/HMGA2 axis

Silencing LINC00987 ameliorates adriamycin resistance of acute myeloid leukemia via miR-4458/HMGA2 axis

Abstract Background Most patients with acute myeloid leukemia (AML) eventually develop drug resistance, leading to a poor prognosis. Dysregulated long gene non coding RNAs (lincRNAs) have been implicated in chemoresistance in AML. Unfortunately, the effects of lincRNAs which participate in regulatin...

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Bibliographic Details
Main Authors: Yue Liu, Xiao-ya Zhu, Li-li Liao, Zhan-hui Zhang, Tao-sheng Huang, Ling Zhang, Xi-wen Jiang, Yi Ma
Format: Article
Language:English
Published: BMC 2024-06-01
Series:Biology Direct
Subjects:
Acute myeloid leukemia
Adriamycin
Long non-coding RNA
microRNA
Online Access:https://doi.org/10.1186/s13062-024-00490-1

Internet

https://doi.org/10.1186/s13062-024-00490-1

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