The Role of C2 Domains in Two Different Phosphatases: PTEN and SHIP2

The Role of C2 Domains in Two Different Phosphatases: PTEN and SHIP2

Phosphatase and tensin homologue (PTEN) and SH2-containing inositol 5′-phosphatase 2 (SHIP2) are structurally and functionally similar. They both consist of a phosphatase (Ptase) domain and an adjacent C2 domain, and both proteins dephosphorylate phosphoinositol-tri(3,4,5)phosphate, PI(3,4,5)P<su...

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Bibliographic Details
Main Authors: Laura H. John, Fiona B. Naughton, Mark S. P. Sansom, Andreas Haahr Larsen
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Membranes
Subjects:
PTEN
SHIP2
phosphoinositol
PIP
MD
C2 domain
Online Access:https://www.mdpi.com/2077-0375/13/4/408

Internet

https://www.mdpi.com/2077-0375/13/4/408

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