Trans-population graph-based coverage optimization of allogeneic cellular therapy

BackgroundPre-clinical development and in-human trials of ‘off-the-shelf’ immune effector cell therapy (IECT) are burgeoning. IECT offers many potential advantages over autologous products. The relevant HLA matching criteria vary from product to product and depend on the strategies employed to reduc...

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Bibliographic Details
Main Authors: Sapir Israeli, Elizabeth F. Krakow, Martin Maiers, Corinne Summers, Yoram Louzoun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1069749/full