A pilot investigation of genetic and epigenetic variation of FKBP5 and response to exercise intervention in African women with obesity

Abstract We investigated gluteal (GSAT) and abdominal subcutaneous adipose tissue (ASAT) DNA methylation of FKBP5 in response to a 12-week intervention in African women with obesity, as well as the effect of the rs1360780 single nucleotide polymorphism (SNP) on FKBP5 methylation, gene expression and...

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Bibliographic Details
Main Authors: Tarryn Willmer, Amberly Oosthuizen, Stephanie Dias, Amy E. Mendham, Julia H. Goedecke, Carmen Pheiffer
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-15678-6