A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis

A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis

Programmed cell death or apoptosis is an essential biological process that is impaired in some diseases and can be used to assess the effectiveness of drugs. Here the authors design Apo-15 as a fluorogenic peptide for the detection and real-time imaging of apoptotic cells.

Bibliographic Details
Main Authors: Nicole D. Barth, Ramon Subiros-Funosas, Lorena Mendive-Tapia, Rodger Duffin, Mario A. Shields, Jennifer A. Cartwright, Sónia Troeira Henriques, Jesus Sot, Felix M. Goñi, Rodolfo Lavilla, John A. Marwick, Sonja Vermeren, Adriano G. Rossi, Mikala Egeblad, Ian Dransfield, Marc Vendrell
Format: Article
Language:English
Published: Nature Portfolio 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17772-7

Internet

https://doi.org/10.1038/s41467-020-17772-7

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