Subcellular localization shapes the fate of RNA polymerase III

Summary: RNA polymerase III (Pol III) plays a vital role in transcription and as a viral-DNA sensor, but how it is assembled and distributed within cells remains poorly understood. Here, we show that Pol III is assembled with chaperones in the cytoplasm and forms transcription-dependent protein clus...

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Bibliographic Details
Main Authors: Kai Tian, Rui Wang, Jie Huang, Hui Wang, Xiong Ji
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472300952X