Combined BRM270 and endostatin inhibit relapse of NSCLC while suppressing lung cancer stem cell proliferation induced by endostatin

Combined BRM270 and endostatin inhibit relapse of NSCLC while suppressing lung cancer stem cell proliferation induced by endostatin

Endostatin (ES, ENDO) has been reported to suppress the growth of tumors while inducing the proliferation of lung cancer stem cells (LCSCs), causing a poor prognosis for lung cancer. In this study, we aimed to clarify whether BRM270 can inhibit the proliferation of cancer stem cells (CSCs). Endostat...

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Bibliographic Details
Main Authors: Yan-hui Gu, Yong-chun Shen, Yao Ou-yang, Xi-min Rao, Dan-dan Fu, Fu-qiang Wen
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
lung cancer
stem cell
BRM270
miR-128
BMI-1
ABCC-5
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770521000772

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http://www.sciencedirect.com/science/article/pii/S2372770521000772

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