Study on the reversibility of olfactory epithelium lesion induced by ZnSO4(ZnSO4损伤嗅上皮可逆性的研究)

为探讨ZnSO4对嗅上皮的损伤是否可逆,以成年SD大鼠为对象,ZnSO4或Triton X-100分别灌流单边鼻孔,用免疫组化技术,检测损伤后30、45和60 d嗅球酪氨酸羟化酶的免疫反应,结果在损伤后30 d,损伤鼻孔同侧嗅球的TH阳性细胞密度明显下降,Triton X-100损伤后45 d的TH阳性细胞密度比30 d时增加,60 d时已接近对照组,但ZnSO4损伤后45、60 d与30 d的结果类似,提示ZnSO4对嗅上皮的损伤是不可逆的....

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Bibliographic Details
Main Authors: QINZhao-ping(秦照萍), YEShu-ming(叶树明), DUJi-zeng(杜继曾), SHENGong-yu(沈公羽)
Format: Article
Language:zho
Published: Zhejiang University Press 2005-09-01
Series:Zhejiang Daxue xuebao. Lixue ban
Subjects:
Online Access:https://doi.org/zjup/1008-9497.2005.32.5.570-573