Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs

Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs

Summary: The premetastatic niche (PMN) contributes to lung-specific metastatic tropism in osteosarcoma. However, the crosstalk between primary tumor cells and lung stromal cells is not clearly defined. Here, we dissect the composition of immune cells in the lung PMN and identify granulocytic myeloid...

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Bibliographic Details
Main Authors: Chuangzhong Deng, Yanyang Xu, Hongmin Chen, Xiaojun Zhu, Lihua Huang, Zhihao Chen, Huaiyuan Xu, Guohui Song, Jinchang Lu, Wenlin Huang, Ranyi Liu, Qinglian Tang, Jin Wang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
CP: Cancer
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724000792

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http://www.sciencedirect.com/science/article/pii/S2211124724000792

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