What is Rate-Limiting During Sustained Synaptic Activity: Vesicle Supply or the Availability of Release Sites
For some types of synapses the availability of release-ready vesicles is a limiting factor during ongoing activity. Synaptic strength in this case is determined both by the recruitment of such vesicles and the probability of their release during an action potential. Here it is argued that not the av...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2010-09-01
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| Series: | Frontiers in Synaptic Neuroscience |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnsyn.2010.00144/full |