Intranasal Zolmitriptan-Loaded Bilosomes with Extended Nasal Mucociliary Transit Time for Direct Nose to Brain Delivery

Intranasal Zolmitriptan-Loaded Bilosomes with Extended Nasal Mucociliary Transit Time for Direct Nose to Brain Delivery

This study aimed at delivering intranasal zolmitriptan directly to the brain through preparation of bilosomes incorporated into a mucoadhesive in situ gel with extended nasal mucociliary transit time. Zolmitriptan-loaded bilosomes were constructed through a thin film hydration method applying Box–Be...

Full description

Bibliographic Details
Main Authors: Mai M. El Taweel, Mona H. Aboul-Einien, Mohammed A. Kassem, Nermeen A. Elkasabgy
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceutics
Subjects:
zolmitriptan
intranasal
bilosomes
sodium deoxycholate
mucoadhesive gel
brain targeting
Online Access:https://www.mdpi.com/1999-4923/13/11/1828

Internet

https://www.mdpi.com/1999-4923/13/11/1828

Similar Items