Promiscuous Binding of Microprotein Mozart1 to γ-Tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation

Promiscuous Binding of Microprotein Mozart1 to γ-Tubulin Complex Mediates Specific Subcellular Targeting to Control Microtubule Array Formation

Summary: How γ-tubulin ring complex (γ-TuRC), a master template for microtubule nucleation, is spatially and temporally regulated for the assembly of new microtubule arrays remains unclear. Here, we report that an evolutionarily conserved microprotein, Mozart1 (Mzt1), regulates subcellular targeting...

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Bibliographic Details
Main Authors: Tzu-Lun Huang, Hsiu-Jung Wang, Ya-Chieh Chang, Shao-Win Wang, Kuo-Chiang Hsia
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Cell Reports
Subjects:
Mozart1
γ-TuRC
microtubule nucleation
microprotein
γ-TuRC targeting
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720308172

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http://www.sciencedirect.com/science/article/pii/S2211124720308172

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