Palmitic Acid Affects Intestinal Epithelial Barrier Integrity and Permeability In Vitro

Palmitic Acid Affects Intestinal Epithelial Barrier Integrity and Permeability In Vitro

Palmitic acid (PA), a long-chain saturated fatty acid, might activate innate immune cells. PA plays a role in chronic liver disease, diabetes and Crohn’s disease, all of which are associated with impaired intestinal permeability. We investigated the effect of PA, at physiological postprandial intest...

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Bibliographic Details
Main Authors: Manuele Gori, Annamaria Altomare, Silvia Cocca, Eleonora Solida, Mentore Ribolsi, Simone Carotti, Alberto Rainer, Maria Francesconi, Sergio Morini, Michele Cicala, Michele Pier Luca Guarino
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Antioxidants
Subjects:
palmitic acid
Caco-2 monolayer
intestinal permeability
gut barrier integrity
tight junctions
adherens junctions
Online Access:https://www.mdpi.com/2076-3921/9/5/417

Internet

https://www.mdpi.com/2076-3921/9/5/417

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