Antimicrobial Potential of Betulinic Acid and Investigation of the Mechanism of Action against Nuclear and Metabolic Enzymes with Molecular Modeling

Antimicrobial Potential of Betulinic Acid and Investigation of the Mechanism of Action against Nuclear and Metabolic Enzymes with Molecular Modeling

Natural products have important pharmacological activities. This study sought to investigate the activity of the compound betulinic acid (BA) against different strains of bacteria and fungi. The minimum inhibitory concentration (MIC) was determined and then the minimum bactericidal concentration (MB...

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Bibliographic Details
Main Authors: Gabriela Cristina Soares Rodrigues, Mayara dos Santos Maia, Thalisson Amorim de Souza, Edeltrudes de Oliveira Lima, Luiz Eduardo Carneiro Gomes dos Santos, Shellygton Lima Silva, Marcelo Sobral da Silva, José Maria Barbosa Filho, Valnês da Silva Rodrigues Junior, Luciana Scotti, Marcus Tullius Scotti
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pathogens
Subjects:
betulinic acid
antimicrobial activity
triterpenoids
<i>M. tuberculosis</i>
<i>E. coli</i>
Online Access:https://www.mdpi.com/2076-0817/12/3/449

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https://www.mdpi.com/2076-0817/12/3/449

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