Increased expression of OPN contributes to idiopathic pulmonary fibrosis and indicates a poor prognosis

Increased expression of OPN contributes to idiopathic pulmonary fibrosis and indicates a poor prognosis

Abstract Background Idiopathic pulmonary fibrosis (IPF) is fibrotic lung disease with no effective treatment. It is characterized by destruction of alveolar structure and pulmonary interstitial fibrosis, leading to dyspnea and even asphyxia death of patients. Epithelial-mesenchymal transition (EMT)...

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Bibliographic Details
Main Authors: Jie Ji, Shudan Zheng, Yuxin Liu, Tian Xie, Xiaoyu Zhu, Yang Nie, Yi Shen, Xiaodong Han
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Translational Medicine
Subjects:
Idiopathic pulmonary fibrosis (IPF)
Prognostic
Osteopontin (OPN)
Alveolar epithelial cell
Epithelial-mesenchymal transition (EMT)
Online Access:https://doi.org/10.1186/s12967-023-04279-0

Internet

https://doi.org/10.1186/s12967-023-04279-0

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